Importance of informing patients of other important precautionary information. Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed. Importance of patients informing clinicians of existing or contemplated therapy, including prescription and OTC drugs, as well as any concomitant illnesses. Importance of avoiding alcohol during therapy. Risk of drowsiness use caution when driving or operating machinery. ActionsĮxhibits CNS depressant, anticholinergic, antiemetic, antispasmodic, and local anesthetic effects in addition to antihistaminic activity.ĭepresses labyrinth excitability and conduction in vestibular-cerebellar pathways.Īntiemetic and antimotion-sickness actions result, at least in part, from central anticholinergic and CNS depressant properties. Tight, light-resistant container at 15–30☌. Stability Storage Oral Capsules and Tablets Elimination RouteĮxcreted in feces as unchanged drug and in urine as norchlorcyclizine. In rats, metabolized (probably in the liver) to norchlorcyclizine. Distribution Extentĭistributed throughout most body tissues crosses placenta. Meclizine drug interactions (more detail) Meclizine Pharmacokinetics Absorption OnsetĮffects persist for 8–24 hours following a single oral dose. Interactions for Meclizine Specific Drugs Common Adverse Effectsĭrowsiness, fatigue, dry mouth. Safety and efficacy not established in children <12 years of age. Due to potential for serious adverse effects (e.g., CNS effects) in nursing infants, discontinue nursing or the drug. Specific Populations PregnancyĪntihistamines may inhibit lactation and small amounts appear to be distributed into milk. Incidence of tartrazine sensitivity is low, but it frequently occurs in patients who have aspirin hypersensitivity. 5), which may cause allergic reactions (i.e., bronchial asthma) in susceptible individuals. ![]() Some formulations contain tartrazine dye (FD&C yellow No. Sensitivity Reactions Tartrazine Sensitivity (See Specific Drugs under Interactions.) Anticholinergic Effectsĭue to potential anticholinergic activity, use with caution in patients with breathing problems (e.g., asthma, emphysema, chronic bronchitis), angle-closure glaucoma, or prostatic hypertrophy. Possible additive CNS depression with other CNS depressants. Warnings/Precautions Warnings CNS Effects Vertigo OralĢ5–100 mg daily, administered in divided doses, depending on clinical response.ĭetailed Meclizine dosage information Cautions for Meclizine Contraindications Adults Motion Sickness Oralįor self-medication, 25–50 mg once daily or as directed by clinician. ![]() Pediatric Patients Motion Sickness Oralįor self-medication in children ≥12 years of age, 25–50 mg once daily or as directed by clinician. DosageĪvailable as meclizine hydrochloride dosage expressed in terms of meclizine. Meclizine Dosage and Administration Administration Oral Administrationįor prevention of motion sickness, administer orally 1 hour before exposure to motion may repeat every 24 hours for duration of journey. ![]() Symptomatic management of vertigo associated with diseases affecting the vestibular system (e.g., labyrinthitis, Ménière’s disease). Self-medication for prevention and treatment of nausea, vomiting, and/or dizziness associated with motion sickness. Written by ASHP.Īntiemetic piperazine-derivative antihistamine. If you no longer wish to have this DailyMed RSS service, simply delete the copied URL from your RSS Reader.Brand names: Antivert, Bonine, Dramamine Less Drowsy, Meni-D ![]() To view updated drug label links, paste the RSS feed address (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X. What will I get with the DailyMed RSS feed?ĭailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed.ĭailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. To receive all DailyMed Updates for the last seven days Meclizine hydrochloride (UNII: HDP7W44CIO) (meclizine - UNII:3L5TQ84570)Ĭopy the URL below and paste it into your RSS Reader application.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |